Disseminated cutaneous leishmaniasis in Old World mimicking histoid leprosy

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Cutaneous leishmaniasis of the Old World.

Cutaneous Leishmaniasis is a vector-borne protozoal infection of the skin. Several species of Leishmania cause this disease in the Old World. It is manifested as chronic nodular to ulcerative lesions of the skin, which last for many months and may be disfiguring. They eventually heal leaving a scar. Local care of the lesion and treatment of secondary bacterial infection are essential for healin...

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Interventions for Old World cutaneous leishmaniasis.

BACKGROUND Cutaneous leishmaniasis, caused by a parasitic infection, is considered one of the most serious skin diseases in many low- and middle-income countries. Old World cutaneous leishmaniasis (OWCL) is caused by species found in Africa, Asia, the Middle East, the Mediterranean, and India. The most commonly prescribed treatments are antimonials, but other drugs have been used with varying s...

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Histoid Leprosy

A 20-year-old young male, an agricultural laborer, complained of multiple asymptomatic shiny nodules all over the body. The lesions were present for the last 1 year. He had two episodes of epistaxis in the last 6 months that were treated symptomatically. The nodules were distributed predominantly over the trunk and thighs. Family history was non-contributory. He did not take any form of treatme...

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Pharmacokinetics of miltefosine in Old World cutaneous leishmaniasis patients.

The pharmacokinetics of miltefosine in leishmaniasis patients are, to a great extent, unknown. We examined and characterized the pharmacokinetics of miltefosine in a group of patients with Old World (Leishmania major) cutaneous leishmaniasis. Miltefosine plasma concentrations were determined in samples taken during and up to 5 months after the end of treatment from 31 Dutch military personnel w...

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Old world cutaneous leishmaniasis infection in children: a case series.

L eishmaniasis currently threatens 350 million people in 88 countries around the world. Ninety per cent of cutaneous leishmaniasis (CL) cases occur in Afghanistan, Brazil, Iran, Peru, Saudi Arabia, and Syria. An epidemic of cutaneous leishmaniasis is ongoing in Kabul, Afghanistan with an estimated 200 000 cases. Lesions can be very disfiguring, particularly on the face, which may have long term...

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ژورنال

عنوان ژورنال: Indian Journal of Dermatology, Venereology and Leprology

سال: 2021

ISSN: 0378-6323

DOI: 10.4103/ijdvl.ijdvl_885_19